View Full Version : Gestational Diabetes and Cranio
12-22-2010, 01:57 PM
As I sit and wonder why my daughter has Craniosynostosis, I can't help but think it may have been caused by the medication I took while I was pregnant with her. I took the drug Glyburide for just 2 days for my gestational diabetes. I had horrible side effects and told my doctor I was going to quit taking it. There was pressure in my uterus, it felt as though I couldn't walk. She wouldn't move, I was dizzy and felt almost as though I was high. It was horrible. I was later put on insulin at night since my most concerning blood sugar number was in the morning after I woke up. The rest of the time I was able to contral it well with my diet.
Wondering if anyone else took this drug while pregnant? Or had Gestational Diabetes. I want to get genetic testing as well, but I have been doing some reading about the Glyburide during pregnancy and one article said it caused bone problems in pregnant animals... that makes me so upset if this drug could have caused my daughter to have this.
12-22-2010, 02:22 PM
I had gestational diabetes but did not take that drug. I was on insulin for a few months. I really don't think that is what caused it. If you do research, you'll find that cranio is usually either a fluke thing or is genetic. And I don't think taking a drug for only 2 days would do it either. Most everything forms in the first 6-8 weeks of pregnancy, so that is the most important time.
12-22-2010, 04:15 PM
I had gestational diabetes and took glyburide (a fairly high dose) for about 8 weeks, but honestly, I don't believe that is what caused it. I think it was just something that happened with no reason why (at least not that we will ever know). It could be positional as Nicholas was "stuck" in the same position under my rib cage for almost the entire pregnancy and he never did turn (he was delivered via c-section for this reason), but I'll never know. It's easier for me to say this because I'm much further along on this cranio rollercoaster ride, but please don't beat yourself up trying to figure out what caused the cranio as it will drive you crazy, and please don't think it was anything you did or any medication you took. I did this with both Nicholas' cranio and then with my twins' premature birth at 28 weeks and I wish I hadn't as it really did drive me nuts and it didn't get me anywhere. I will never know what caused either of these things. All I do know is that I did everything I could to ensure a healthy pregnancy and I'm sure the same is the case for you. Cranio is a very difficult journey, but you will get through his and your little one will be fine - she will amaze you at how strong she is!
12-22-2010, 09:51 PM
I had gestational diabetes with Harper, I only ever used insulin but only for the last 4 weeks. Our hospital doesn't do genetic testing unless you specifically ask for it and I think with Harper it was just one of those things. I haven't heard of Glyburide but I would have thought it wouldn't be prescribed duing pregnancy if it wasn't safe, but you never know do you. Even if it did cause the cranio (which it probably didn't) it isn't your fault at all, you did the right thing by stopping taking it when things didn't feel right.
12-23-2010, 08:25 AM
I also had GD, but was only on insulin the last couple weeks of my pregnancy. I only had to give it to myself at night because my numbers were high in the morning. I never had to take the drug you mentioned. I went back and looked at my 20 week ultrasound pictures and noticed the oblong shaped had and pronounced forehead. So this was before I was diagnosed with GD.
12-23-2010, 01:07 PM
I did not have gestational diabetes, but was tested 3 times before they ruled it out. I did however, take glucophage for my entire pregnancy. I have PCOS and it was prescribed to help with infertility. Once pregnant, my OB GYN said to continue taking it so as not to "disrupt" anything. I have often wondered about this but will never know :)
04-28-2011, 11:08 AM
I had Gestational Diabetes, but didn't need to take any meds/insulin, just had to watch my diet.
05-01-2011, 06:59 PM
I did not have GD but I failed the 1 hr test and only passed the 3hr test by a VERY thin margin...I was told I had an "apparent glucose intolerance" and never took anything they just said to watch my diet.
07-11-2011, 03:04 AM
I find it interesting how many people seem to have had GD and their kids have Cranio. I also had GD, and I was on a LOT on insulin from 28-37 weeks pregnant (DD was delivered at 37 weeks.) I wonder if there does happen to be a correlation....
07-11-2011, 09:33 AM
We are certain now that Brynn's cranio is because of the syndrome she likely has. Although, I do think that there is probably some link between GD and cranio. I think it should be researched more. I still get irritated when I think of taking Glyburide and how horrible it made me feel. I told my doctor there is no way I was going to take it anymore. I just had a bad feeling about it. My blood sugars dropped so low and after that, Brynn was in a really weird position and didn't move as much anymore for the rest of the pregnancy. I wonder if blood sugars play a role in it sometimes?
07-11-2011, 09:52 AM
I was borderline GD, I barely failed the 3 hour test. I just watched my diet. I did notice that Bella hardly moved and my first was a football player inside me. I think it was maybe her position.
07-11-2011, 04:01 PM
I also had gestational diabetes while pregnant for Matthew, but I didn't with my older two. I didn't have to take any meds of insulin. It was controlled by diet. I wondered if it could have been linked, but I can't find any resources that claim that.
07-11-2011, 09:37 PM
No gestational diabetes here and my daughter has Sagittal. Just thought I would add this to the bunch.
07-11-2011, 10:34 PM
I didn't have GD's either. I did have pregnancy induced hypertention, but I didn't take any meds during pg.
07-13-2011, 02:05 PM
On top of having GD I also was diagnosed with mild preeclampsia so who knows!
07-14-2011, 08:34 AM
No gestational diabetes here, I know a few women who've had GD and none of their children have cranio.
07-14-2011, 01:47 PM
Wow - I had gestational diabetes with both of my children. First child seems to be fine, he is three years old. It is my second baby we are worried about and I took insulin with her pregnancy only for the last 6 weeks.
07-18-2011, 05:33 PM
I also had gestational diabetes while pregnant for Malu, and she did a lot of hiccups while in my tum.
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